Invited Speakers
A preliminary list of confirmed speakers

Dame Professor Molly Stephens FRS FREng
University of Oxford, UK Kavli Institute for Nanoscience Discovery Department of Physiology, Anatomy and Genetics Department of Engineering Science
University of Oxford
UNITED KINGDOM
About
Professor Dame Molly Stevens FREng FRS is John Black Professor of Bionanoscience at the University of Oxford, and also holds part-time professorships at Imperial College London and the Karolinska Institute.
Read more
Professor Stevens’ multidisciplinary research balances the investigation of fundamental science with the development of technology to address some of the major healthcare challenges. She is a serial entrepreneur and the founder of several companies in the diagnostics, advanced therapeutics and regenerative medicine space. Her work has been instrumental in elucidating the bio-material interfaces. She has created a broad portfolio of designer biomaterials for applications in disease diagnostics and regenerative medicine. Her substantial body of work influences research groups around the world (>450 publications, h-index 123, >58k citations, Clarivate Analytics Highly Cited Researcher in Cross-Field research).
Professor Stevens holds numerous leadership positions including Deputy Director of the Kavli Institute for Nanoscience Discovery and the UK Quantum Biomedical Sensing Research Hub, and Scientist Trustee of the National Gallery. She is Fellow of the Royal Society and the Royal Academy of Engineering (UK), Foreign Member of the National Academy of Engineering (USA), International Honorary Member of the American Academy of Arts and Sciences, and she has been recognised with over 30 international awards including the 2023 Novo Nordisk Prize.

Professor Liam Grover
Professor in Biomaterials Science, Head of School of Chemical Engineering, and Director of the Healthcare Technologies Institute (HTI)
University of Birmingham
UNITED KINGDOM
About
Professor Liam Grover is a Professor in Biomaterials Science and the Director of the Healthcare Technologies Institute, an interdisciplinary network of over 70 academics.
Read More
This network includes chemical engineering, biomedical science, computer science, applied mathematics, chemistry and physics, working together to advance new technologies and treatments that encourage better tissue healing and rehabilitation tools for healthcare applications.
Professor Grover is a materials scientist by training, and completed his PhD at the University of Birmingham before moving to McGill University (Montreal), to work as a CIHR skeletal health scholar. He returned to Birmingham in 2006 to establish a research group within the School of Chemical Engineering. He has published widely on the development of new materials to replace the function of tissues (more than 180 papers) and has filed more than ten patents to protect technologies that range from osteogenic cements through to scar reducing dressings; and progressed three technologies from concept through to clinical trials.
He was the youngest Professor in the history of the University of Birmingham (32) and the youngest ever Fellow of the Institute of Materials (30). Since returning to Birmingham, he has raised over £30m to fund his research on the development and translation of novel medical technologies and is the Founder-Director of the Healthcare Technologies Institute.

Professor Paul Genever
Professor of Stem Cell Biology, Department of Biology, Co-founder and CSO of Mesenbio
University of York & Mesenbio
UNITED KINGDOM
About
Professor Paul Genever is Professor of Stem Cell Biology, with research interests in the cell and molecular biology of skeletal tissues in health and disease.
Read More
He specifically focussed on the characterisation of heterogeneous bone marrow mesenchymal stromal cells (MSCs), stem cell fate and the control of differentiation, tissue remodelling and regeneration. Ultimately, Professor Genever and his Team aims to exploit our understanding of MSC biology and their secreted products, including extracellular vesicles (EVs), to develop new treatments for degenerative and inflammatory disorders.
With this aim, Professor Genever established Mesenbio, a preclinical stage biopharmaceutical company from the University of York, to help accelerate the translation of their stromal cell EV therapeutics with combined anti-inflammatory and pro-regenerative properties into patients with musculoskeletal disease.

Professor Matthew Hardman
Chair in Wound Healing and Director of Research, Faculty of Health Sciences, Hull York Medical School
University of Hull
UNITED KINGDOM
About
Professor Matthew Hardman has more than 20 years’ experience in the field of skin biology, with a specific focus on wound healing.
Read More
He obtained his PhD in Cell and Molecular Biology from the University of Manchester in 2000, being appointed Senior lecturer and Senior Research Fellow at the University of Manchester in 2007, where he was also Director of the EPSRC & MRC Centre for Doctoral Training in Regeneration Medicine. In 2016, Professor Hardman was appointed Reader in Wound Healing at the University of Hull, being promoted to Professor in 2018.
Professor Hardman’s research spans basic biology through to clinical studies, being funded by the Medical Research Council, National Institutes of Health and a number of charities. His wound healing group also engages with a number of industry partners and the Hull and East Yorkshire Hospitals NHS Trust, ensuring a clear route to patient benefit.

Dr Claire Higgins
Reader in Tissue Regeneration, Department of Bioengineering, Faculty of Engineering
Imperial College London
UNITED KINGDOM
About
Dr. Claire Higgins joined the Department of Bioengineering in April 2014 after postdoctoral training in the Department of Dermatology, at Columbia University in New York.
Read More
At Columbia, she received a Career Development Award from the Dermatology Foundation to research the ‘Molecular basis of human hair follicle induction’. Claire obtained a PhD in Skin Developmental Biology from Durham University in 2007, and holds a BSc in Natural Sciences. She is currently a Reader in Skin Regeneration within the Department. The focus of the Research Group is to understand mechanisms of tissue development, and regeneration, both in normal conditions, and in response to disease or injury. The hair follicle is used as a model, as it is an accessible and elegant system to study organ regeneration. Research into developmental, and regenerative processes means we can try and recreate them in a lab setting, and exploit the inherent properties of interacting cells to engineer new tissues and structures. Hair follicles contain specialised cells located in a small mesenchymal compartment at the base of the follicle, termed the dermal papilla. Interaction between the dermal papilla and the bulge (the epithelial stem cell compartment of the follicle), drives the hair follicle cycle. Work in the lab encompasses understanding how these cells acquire their specialised ability to instruct hair growth, in addition to elucidating the role of these cells in response to traumatic injury, and their behaviour during skin repair.

Dr. Paul Reddell
Co-Founder and Chief Scientific Officer
QBiotics Group AUSTRALIA
About
Dr Paul Reddell is Chief Scientific Officer of Australian life sciences company, QBiotics Group, which is developing ‘plant-inspired’, small signalling molecules as drugs for use in a range of therapeutic areas, including wound healing.
Read More
Dr Reddell leads the company’s multidisciplinary portfolio of in-house and university-contracted discovery and translational research projects. The company’s most advanced products are in oncology (a small molecule in Phase II clinical trials in the UK, Australia and the USA for treatment of head and neck cancers and soft tissue sarcomas) and wound healing (EBC-1013 in a Phase I safety trial in Australia in patients with venous leg ulcers). Prior to co-founding QBiotics, Dr Reddell held numerous roles in government, industry and academia including as Senior Principal Research Scientist in the Australian Government’s Scientific Research Organisation (CSIRO), an independent member of the Australian Department of Health’s Gene Technology Technical Advisory Committee, Professorships at Oregon State University and the University of Hong Kong, and a Post-doctoral Fellowship at the University of Bristol. Dr Reddell holds a PhD from the University of Western Australia and was appointed a Fellow of the Australian Institute of Company Directors, for his role in facilitating translation of basic scientific research into commercial opportunities.

Professor Tero Järvinen
Professor and Chief Surgeon, Department of Orthopedics and Traumatology
Tampere University Hospital
FINLAND
About
Dr. Tero Järvinen is the Professor and the Chief Surgeon at the Tampere University and the Tampere University Hospital, Finland. Professor Järvinen graduated from Medical School and received his PhD Thesis in cancer genetics at Tampere University.
Read More
He completed his clinical training in orthopaedics and traumatology. Between 2003-2006, he undertook postdoctoral studies with the world-renowned cell biologist, Professor Erkki Ruoslahti, at the Sanford Burnham Prebys Medical Discovery Institute at the University of California, La Jolla; and later worked as a Visiting Professor at the University of California at Santa Barbara (UCSB). With strong research interests in tissue regeneration and multi-functional therapeutics to enhance tissue repair, Professor Järvinen has published almost 150 peer-reviewed papers, among them articles in the journals such as Nat. Comms., PNAS, Mol. Ther., and the NEJM. His research has been cited almost 16,000 times (H-index 54).

Professor Susan Volk
Corinne R. and Henry Bower Professor of Surgery, Bioengineering Graduate Group, School of Veterinary Medicine
University of Pennsylvania
USA
About
Professor Volk is Professor of Small Animal Surgery at the University of Pennsylvania School of Veterinary Medicine Philadelphia, USA. She completed her VMD and PhD degrees, as well as a small animal surgical residency, at the University of Pennsylvania, and is board-certified by the American College of Veterinary Surgeons.
Read More
As a veterinary surgeon, Professor Volk’s clinical interests focus on surgical oncology, cutaneous wounds and their reconstruction, with specific expertise in regenerative medical therapies. Such research activities are complimented by a basic research programme focused on understanding the regulatory mechanisms governing dynamic interactions between cells and their surrounding extracellular matrix in both regenerative and tumor microenvironments, and to apply this knowledge to develop innovative regenerative and oncologic therapies for veterinary and human patients.
In addition to being an active member of several national and international societies, Professor Volk will be elected President of the Wound Healing Society (WHS) at it’s meeting in April-May 2025.

Professor Denis Barritault
Emeritus Professor and Honorary Director of the CRRET Unit
OTR3
FRANCE
About
Professor Barritault has been President of OTR3 since 2004, a Biotechnology Company in the field of regenerative medicine.
Read More
He graduated in Physics from Nante University and completed his PhD in Biochemistry from Paris University, France. He undertook Postdoctoral studies in Molecular Immunology at Pasteur Institute and the NYU. As a NIH Fogarty Fellow, he joined the INSERM Unit in Paris as a Developmental Biologist. Between 1982-2003, he was a Full Professor at Paris-Est University and also founded and directed a CNRS Laboratory in cell and tissue regeneration, until 2003. Since 2004, he has been Emeritus Professor and Honorary Director of the CNRS laboratory CRRET. Professor Barritault currently has over 200 publications and 40 patents.

Dr. Oommen Oommen
Lecturer in Biomaterials and Nanomedicine, School of Pharmacy and Pharmaceutical Sciences
Cardiff University
UNITED KINGDOM
About
Dr. Oommen received his PhD in Chemistry from the Indian Institute of Technology-Bombay in 2010.
Read More
He, then moved to Uppsala University, Sweden to pursue his Postdoctoral studies in the field of regenerative medicine. In 2016, he joined Tampere University, Finland, as a tenure-track Assistant Professor, establishing the Bioengineering and Nanomedicine Group, and became Associate Professor in 2020. In July 2024, he joined Cardiff University’s School of Pharmacy as a Lecturer. His multidisciplinary research focuses on biomaterials, nanomedicine, and tissue engineering. He developed ECM mimetic nanoparticles that effectively penetrate blood-brain barrier and suppress glioma growth in PDX models. He is developing novel bioconjugation strategies to develop advanced 3D scaffolds for tissue engineering and 3D bioprinting. He is currently developing physiologically relevant 3D tumour microenvironment (TME) models (prostate TME and brain TME), to study intricate immune-cancer interactions.

Dr. Soma Meran
Clinical Reader in Nephrology and Head of the Wales Kidney Research Unit
School of Medicine, Cardiff University
UNITED KINGDOM
About
Dr Soma Meran is a Clinical Reader at Cardiff University’s School of Medicine, who heads the Wales Kidney Research Unit Laboratories in Cardiff and holds an Honorary Consultant Nephrologist post with the University Hospital of Wales.
Read More
Her main research interests are in the field of renal fibrosis. Her Group aims to understand and delineate the mechanisms that can prevent and/or reverse acute and progressive kidney injury, leading to improved kidney health. The extracellular matrix plays an important role in maintaining biological health in cells and tissues and aberrant extracellular matrix regulation drives disease, particularly in the kidneys. Her research has shown that the extracellular matrix glycosaminoglycan, hyaluronan, is important in regulating stromal cell phenotype and function to influence renal health and disease. Her studies focus on how this matrix component can be regulated to improve kidney recovery, following injury and disease. Parallel research areas include peritoneal dialysis research (understanding mechanisms that drive fibrosis in the peritoneum) and cardiorenal research (understanding the cellular and molecular drivers of increased cardiovascular pathology in patients with kidney disease).

Dr. Maki Umemura
Reader in International Management and Business History, Cardiff Business School
Cardiff University
UNITED KINGDOM
About
Dr Maki Umemura is a Reader in International Management and Business History. Her research has been concerned with the evolution of industries at the technological frontier.
Read More
Maki has expertise in the political economy of biomedical innovation and the healthcare industry, including regenerative medicine.
Maki has attracted funding on projects relating to different aspects of innovation, including the Wellcome Trust, the Japan Foundation Endowment Committee and the Michelin Fellowship. She also been a visiting researcher at the Department of Political Economy at King’s College London, and the École des hautes études en sciences sociales (EHESS) in Paris. Maki is the Alfred D. Chandler Jr. International Visiting Scholar in Business History at Harvard Business School for 2023.
Maki is a member of the Society for the Advancement of Socioeconomics, the Business History Conference, the Association of Business Historians and the Academy of Management. She is also on the editorial board of the journal, Business History. She is Chair of the Business School’s Entrepreneurship and Innovation Forum and a member of the People Committee.

Dr Matthew Malone
Director of Medical Affairs
Convatec Wound Care
UNITED KINGDOM
About
Read More

Dr Lindsay Davies
Chief Scientific Officer
NextCell Pharma
SWEDEN
About
Lindsay Davies completed her PhD in biochemistry in 2006 at Cardiff University, UK. Focussing on cell therapy for cartilage repair, her Thesis work introduced her to cell and gene therapy, springboarding her into a career within the field, starting with a Postdoctoral and two Fellowship positions in stem/stromal cell biology within the UK.
Read More
During this time, Dr Davies discovered a novel stem cell population within the oral cavity, which she patented and won multiple awards related to this work.
She subsequently moved to Karolinska Institutet, Sweden. As an Associate Professor, Dr Davies worked with basic science and clinical trial development using stromal cells from different tissue sources. Alongside her academic work, she worked with the Finnish Red Cross Blood Service and an industrial partner in developing a new medical device for burns therapy. In 2020, Dr Davies moved into industry setting up her own consulting company, CellTherEx, to support academics and companies spinning out and handling regulatory compliance within the drug discovery and advanced therapeutic development space. This offered her the opportunity to join NextCell Pharma, a cell therapy company, developing stromal cell products for usage in multiple clinical indications. As their Chief Scientific Officer, she has supported the company´s movement from a phase I company, with one initial clinical trial to 5 active Phase I/II trials, international expansion and a phase III in development. In 2024, Dr Davies co-founded QVance, a subsidiary of NextCell Pharma, specialising in quality control analytics service provision for advanced therapy developers. The company was launched in November 2024 and aims to be a “one-stop-shop” analytics company serving the Nordics and wider Europe.
Dr Davies continues to work closely with academia in the space of wound healing and cell therapy development. In addition to her academic and industrial roles, Lindsay is European Secretary for the ISCT, sitting on the European Task Force and several committees related to process development and commercialisation. She is also an industry representative for the Swedish national ATMP coordinating team and member of several scientific advisory boards for European societies and corporate entities.

Dr Ning Xu Landen
Associate Professor in Experimental Dermatology and Venereology, Unit of Dermatology, Department of Medicine
Karolinska Institute
SWEDEN
About
Ning Xu Landén was born in China in 1980. She earned her Bachelor of Medicine from Peking University in 2003 and completed her PhD in Medical Virology at Uppsala University, Sweden, in 2008.
Read More
She then conducted postdoctoral research at Karolinska Institutet (KI) from 2009-2013, before establishing her research group as an Assistant Professor in 2013. She became a Docent in Experimental Dermatology in 2017, and has been a Senior Lecturer at KI since 2022. Dr. Xu Landén has received numerous prestigious awards, including the LEO Foundation Award, a global recognition for outstanding contributions to dermatology research. Her research combines single-cell multiomics, functional genomics, and RNA-based therapies to identify new molecular targets for wound treatment and develop novel strategies to restore normal healing.

Dr Laura Howard
Postdoctoral Researcher, School of Optometry and Vision Sciences
Cardiff University
UNITED KINGDOM
About
Dr Howard is a Postdoctoral Researcher at Cardiff University. She earned her PhD in Developmental Biology from the University of Warwick and subsequently joined the School of Biosciences at Cardiff University,
Read More
where she investigated the factors influencing the growth and elaboration of neural processes during early development. In 2020, she moved to the School of Optometry and Vision Sciences, where her research has focused on deciphering the transcriptomic landscape of eye-like structures generated in vitro from human induced pluripotent stem cells (hiPSCs). This work has been conducted in collaboration with researchers from Osaka, Japan, where the first in-human transplants using these re-programmed stem cell constructs were recently performed, resulting in substantial improvements in vision for sight-impaired individuals.

Professor Tim Bowen
Professor of Matrix and Molecular Biology, Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, Cardiff University, UK
Cardiff University
UNITED KINGDOM
About
Professor Tim Bowen is Professor of Matrix and Molecular Biology at the Wales Kidney Research Unit, at Cardiff University’s School of Medicine.
Read More
He obtained his PhD from the University of East London in 1990, and following Postdoctoral positions at Cambridge University, University of Leicester and Cardiff University, Dr Bowen was appointed Lecturer in Matrix & Molecular Biology in 2001, being promoted to Professor in 2023.
The central theme of Dr Bowen’s research is the regulation of gene expression in kidney disease. This involves understanding how gene sequences in the human genome give rise to functional RNA and protein products. This knowledge is then translated to inform novel approaches to diagnosis, prognosis and treatment of kidney disease. Gene products have potential utility as kidney disease biomarkers, i.e. sentinels of disease occurrence and/or progression, and as targets for therapeutic intervention. In this context, we are interested in functional RNAs including protein coding RNAs, microRNAs and long noncoding RNAs, as well as proteins and the functional molecules that they synthesise, such as hyaluronan, a glycosaminoglycan of the extracellular matrix. Current research projects include analysis of urinary microRNAs as biomarkers for diabetic kidney disease, immunoglobulin A nephropathy, acute kidney injury, peritoneal fibrosis and renal transplantation outcomes. Investigation into the roles of microRNAs and long noncoding RNAs in mechanisms of kidney disease, including renal fibrosis, is also ongoing.#

Professor David Thomas
Professor and Honorary Consultant in Oral & Maxillofacial Surgery
Advanced Therapies Group, School of Dentistry, Cardiff University
UNITED KINGDOM
About
Professor Thomas is the Professor and Honorary Consultant in Oral & Maxillofacial Surgery at the School of Dentistry, Cardiff University.
Read More
Professor Thomas obtained his BDS Degree from Cardiff University, followed by a PhD at the University of Bristol in 1993, whilst undertaking a Wellcome Trust-funded, Clinical Research Fellowship. Upon returning to Cardiff as a Registrar/Lecturer in Oral & Maxillofacial Surgery, Professor Thomas established his Research Goup, embarking on projects involving various aspects of oral and dermal wound healing and nanomedicine development. This research has received >£15M in funding from various sources worldwide, leading to numerous filed patents with industrial collaborators and therapy development through clinical trial assessment.
Presentation Title: THE APPLICATION OF THE EPOXYTIGLIANE, EBC-1013, IN THE TREATMENT OF INFECTED WOUNDS: DEFINING THE ORTHOGONAL MECHANISMS OF ACTION

Dr Jason Cullen
Principal Scientist
QBiotics Group
AUSTRALIA
About
Dr. Jason Cullen is Principal Scientist at QBiotics Group Ltd. A biochemist/molecular biologist by training, he performed his D.Phil studies (funded by a Medical Research Council awarded studentship) at the University of Oxford, before undertaking a postdoctoral position at QIMR Berghofer (Brisbane, Australia).
Read More
His work has encompassed various areas, ranging from understanding the role of the DNA damage response (DDR) in carcinogenesis, to investigating how defects in genes with roles in DDR/mitochondrial function give rise to neurodegenerative disease. Dr. Cullen is now helping to guide discovery efforts at QBiotics Group Ltd. and is also intimately involved in understanding the mode/mechanism of action of a family of compounds known as the epoxytiglianes, principally in the areas of oncology and in the treatment of chronic/infected wounds. He has aided QBiotics in obtaining over AUD$50M in funding from both governmental and private investment firms and has also authored several papers and patents (the latter now awarded in several territories), centred around the use of the epoxytigliane family in both oncology and tissue repair applications.
Presentation Title: INVESTIGATING EPOXYTIGLIANE-MEDIATED IMMUNOMODULATORY PROCESSES IN THE CONTEXT OF CHRONIC WOUND HEALING.

Dr Emma Woods
Postdoctoral Researcher
QBiotics Group
AUSTRALIA
About
Dr. Woods is a Postdoctoral Researcher employed by QBiotics Group, Australia, but based at Cardiff University, UK. She graduated with a BSc (Hons) degree in Forensic Science from the University of South Wales in 2009,…
Read More
before completing a MSc in Tissue Engineering (2011) and a PhD in myofibroblast cell signalling mechanisms at Cardiff University (2016). Between 2016-2021, Dr Woods undertook several Postdoctoral positions related to myofibroblast cell biology, scarring and drug development at the School of Dentistry and Welsh Kidney Research Unit, Cardiff University. Her current research focuses on deciphering the cell signalling mechanisms involved in mediating epoxytigliane responses in chronic wound fibroblasts, with a particular interest in the effects of epoxytiglianes on downstream kinase signalling.
Presentation Title: CHRONIC WOUND FIBROBLAST RESPONSIVENESS TO STIMULATED REPAIR MECHANISMS BY EPOXYTIGLIANES IS DEPENDENT ON FIBROBLAST KINOME PROFILES.

Professor Ryan Moseley
Professor in Tissue Repair, Disease Mechanisms Group
School of Dentistry, Cardiff University
UNITED KINGDOM
About
Professor Moseley is the Professor in Tissue Repair at the School of Dentistry, Cardiff University. He graduated with BSc (Honours) degree in Biochemistry from Swansea University in 1991,…
Read More
before obtaining his Medical Research Council (MRC)-funded, PhD at the School of Dentistry, University of Wales College of Medicine (UWCM) in 1996. Following Postdoctoral Researcher positions at UWCM/Cardiff University, he was appointed Lecturer in Tissue Repair within the School of Dentistry, being promoted to Senior Lecturer in 2012, Reader in 2017, and Professor in 2022. As Leader of the Disease Mechanisms Group, Professor Moseley’s research specialises in the mechanisms underlying cellular wound healing responses in oral and dermal tissues during health and disease. By understanding these mechanisms, his Research Group develops novel biomaterial, pharmaceutical and other strategies to promote normal tissue repair and improved wound management in these patients. Such research activities have been supported by research funding organisations and industrial partners within the wound healing sector worldwide, culminating in numerous published manuscripts, filed patent and conference prizes.
Presentation Title: EPOXYTIGLIANE STIMULATION OF KERATINOCYTE WOUND HEALING RESPONSES PROMOTE ENHANCED RE-EPITHELIALISATION

Dr Alan Horner
Head of Translational Science (MACA) and Founder of Horner Scientific Consulting
Convatec Global Development Centre
UNITED KINGDOM
About
Dr Horner has nearly 40 years’ experience in R&D and commercialisation. He spent the first 16 years of his career in academia, before transitioning into industry in 2004.
Read More
He holds a PhD from the University of Cambridge, with his PhD and postdoctoral career at the University of Cambridge and NIH Bethesda (USA) focused on the identification and characterisation of cell and molecular mechanism as potential targets for therapeutic intervention for skeletal diseases and disorders. During his industrial career Dr Horner has held numerous positions in multinationals and start-up companies, developing medical devices, biologics, pharmaceuticals and combination products predominantly for musculoskeletal diseases, skin diseases and trauma. He has been involved in the developed technologies from concept to full launch, identified and lead technical diligence and acquisition of external technologies from both SMEs and other global players into multinational organisations. Dr Horner was also part of the team that successfully developed a novel technology platform in the start-up space to acquisition by a global market leader. Additionally, he has driven market access and commercial success through evidence lead commercial strategies, worked closely with regulatory specialists to deliver compliant technical documentation to EU, US and Australian authorities. Recently he developed the clinical strategy for global market introduction and reimbursement (one clinical study is currently actively recruiting and another is currently under review (IDE-RCT), for a novel wound care technology developed as a start-up. Throughout his career, Dr Horner has worked cross-functionally with HCPs, marketing, sales, regulatory, clinical, market access and health economics, to develop integrated strategies to maximise the potential for commercial success be that product launch and sales or divestment to a larger commercial organisation.
Presentation Title: WHAT DOES MEDTECH LOOK FOR IN TERMS OF THE DEVELOPMENT AND COMMERCIALISATION OF NEW WOUND HEALING THERAPIES?